For adults with moderately to severely active ulcerative colitis
DOSING
Just 1 Injection, Every 4 Weeks After 3 Starter Injections
SIMPONI® requires just 12 maintenance injections under the skin after your 3 initial starter injections during the
first year of treatment. Humira® (adalimumab), another leading TNF blocker, requires almost twice as many
maintenance injections during the first year of treatment.
SIMPONI® (golimumab)*†
INDUCTION
Week 0
Week 2
MAINTENANCE
1 injection every 4 weeks
15
TOTAL INJECTIONS PER FIRST YEAR
Humira® (adalimumab)†‡
INDUCTION
Day 1
Day 15
MAINTENANCE
1 injection every 2 weeks
28
TOTAL INJECTIONS PER FIRST YEAR*§
This chart is not intended to compare the safety, effectiveness, or uses of these treatments. While dosing may be important, there are other factors to consider. Talk to your healthcare provider about treatment options and what might be right for you.
*SIMPONI® and Humira®† are also available in a prefilled syringe.
†Trademarks are the property of their respective owners.
‡Humira® is indicated for the treatment of moderately to severely active ulcerative colitis in adult and pediatric patients 5 years of age and older.
§Number of Humira® induction injections calculated using a 80-mg/0.8-mL single-use prefilled pen.
Treatment with SIMPONI® begins with 3 starter injections: 2 injections on your first day of treatment, followed by 1 injection 2 weeks later. After these 3 starter injections, SIMPONI® requires just 1 injection every 4 weeks. If your healthcare provider decides that you or a caregiver may be able to give your injections of SIMPONI® at home, you should receive training on the right way to prepare and inject SIMPONI®. Do not try to inject SIMPONI® yourself until you have been trained to give the injections by your healthcare provider.
Your doctor should test you for TB and hepatitis B before starting SIMPONI®. Your doctor should monitor you closely for signs and symptoms of TB during treatment with SIMPONI®.
SUBCUTANEOUS (UNDER THE SKIN) DOSING OPTIONS
SIMPONI® Offers 2 Easy-to-Use Injection Options
If your healthcare provider decides that you or a caregiver may be able to give your injections of SIMPONI® at home, you should receive training on the right way to prepare and inject SIMPONI®. Do not try to inject SIMPONI® yourself until you have been trained to give the injections by your doctor or nurse.
Always read the Instructions for Use before using your SIMPONI® SmartJect® injector and each time you get a refill. There may be new information.
SmartJect® Autoinjector Specially Designed to Keep the Needle Out of Sight
The SmartJect® autoinjector is specially designed to help you self-inject—without ever having to see the needle. The SmartJect® autoinjector has an easy-to-grip, oval-shaped body and a button on the side that takes only a simple squeeze to inject SIMPONI® under the skin.
Other built-in features include:
- A thin needle that remains hidden throughout the injection process
- A safety sleeve that has to be pressed firmly against the skin for the medicine to inject
- A yellow indicator that appears in the viewing window when you have finished injecting to let you know the autoinjector has worked properly
Video: Injecting with SmartJect® Autoinjector
Video: Injecting with SmartJect® Autoinjector
The SIMPONI® Prefilled Syringe
As with theSmartJect® injector, if your healthcare provider decides that you or a caregiver may be able to give your injections of SIMPONI® at home, you should receive training on the right way to prepare and inject SIMPONI®. Do not try to inject SIMPONI® yourself until you have been shown the right way to give the injections by your doctor or nurse.
Always read the Instructions for Use before using your SIMPONI® prefilled syringe and each time you get a refill. There may be new information.
Video: Injecting with Prefilled Syringe
Please refer to the Medication Guide and Instructions for Use, included with your SIMPONI® medicine, for more information on injecting with SIMPONI® prefilled syringe or SmartJect® Autoinjector.
SIMPONI® is intended for use under the guidance and supervision of a doctor.
Getting SIMPONI® From a Specialty Pharmacy
Biologic medicines like SIMPONI® require special handling. Specialty pharmacies have experience managing these medicines.
1
Doctor
writes prescription and sends it to a specialty pharmacy
2
Specialty pharmacy
calls you about your insurance coverage and potential out-of-pocket costs
3
Specialty pharmacy
arranges delivery of your medicine
For your convenience, the specialty pharmacy can have your SIMPONI® delivered directly to you. Or, if you prefer, your medicine can be shipped to a treatment center—such as your doctor's office or a hospital—and you can pick it up yourself.
Medicine cost support is available. Learn more.
Biologics are medicines that are genetically engineered from products of living organisms, such as proteins, genes, or antibodies.