Get Started With the SIMPONI® Treatment Experience

SIMPONI® is a TNF blocker given as an injection each month for adults with:

  • Moderately to severely active rheumatoid arthritis (RA) in combination with methotrexate
  • Active psoriatic arthritis (PsA) alone or with methotrexate
  • Active ankylosing spondylitis (AS)

AT WEEK 14

In a medical study, more than 5 out of 10 patients (55%) treated with SIMPONI® had at least a 20% improvement in RA symptoms (joint pain, stiffness, and swelling) at 14 weeks compared to placebo.

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Individual results may vary.

Methotrexate is used as directed.

How Does SIMPONI® Work?

Before starting a new medication, it's important to know what it is and how it works. Here's a closer look at SIMPONI®.

SIMPONI® is a TNF blocker biologic medicine

It targets and blocks a protein called TNF-alpha (tumor necrosis factor-alpha).

  • TNF-alpha is made by your immune system
  • People with certain autoimmune diseases have too much TNF-alpha
  • These diseases include:
    • Rheumatoid arthritis
    • Psoriatic arthritis
    • Ankylosing spondylitis
  • Too much TNF-alpha can cause your immune system to attack parts of the body
  • This can lead to the familiar symptoms you feel

SIMPONI® targets and binds with extra TNF-alpha. This helps to block an underlying cause of the symptoms. It can bind with 2 forms of TNF-alpha, and it can bind at more than 1 location.

SIMPONI® targets, binds with, and blocks excess TNF-alpha, helping to control inflammation

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Blocking too much TNF-alpha can make it harder for your body to fight infections. See your doctor regularly. Tell him or her if you have side effects.

SIMPONI® is not for everyone. Only your doctor can decide if SIMPONI® is right for you.

SIMPONI® Offers 2 Easy-to-Use Injection Options

There are 2 different devices you can choose from to administer SIMPONI®. Each one has been awarded an Ease-of-Use Commendation from the Arthritis Foundation®.

Once you and your doctor decide which injection device is best for you and are comfortable with the self-injection process, you can inject SIMPONI® under the skin, once a month with an easy-to-use injection device.

SmartJect® Autoinjector Specially Designed With Patients in Mind

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The SIMPONI® Prefilled Syringe

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If your doctor decides that you or a caregiver may be able to give your injections of SIMPONI® at home, you should receive training on the right way to prepare and inject SIMPONI®. Do not try to inject SIMPONI® yourself until you have been shown the right way to give the injections by your doctor or nurse.

You should always read the Instructions for Use that come with your injector device and each time you get a refill. There may be new information.

Click here for more information on taking SIMPONI®

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Please read the Important Safety
Information about SIMPONI® below, and the Medication Guide, and talk with your doctor.