How Does SIMPONI® Work?
Before starting a new medication, it's important to know what it is and how it works. Here's a closer look at SIMPONI®.
SIMPONI® targets and blocks TNF-alpha
SIMPONI® is an anti-TNF biologic medicine. It targets and blocks a protein called TNF-alpha (tumor necrosis factor-alpha).
- TNF-alpha is made by your immune system
People with certain autoimmune diseases have too much TNF-alpha.
These diseases include:
— Rheumatoid arthritis
— Psoriatic arthritis
— Ankylosing spondylitis
- Too much TNF-alpha can cause your immune system to attack parts of the body
- This leads to the familiar symptoms you feel
SIMPONI® targets and binds with extra TNF-alpha. This helps to block an underlying cause of the symptoms. It can bind with 2 forms of TNF-alpha, and it can bind at more than 1 location.
Blocking too much TNF-alpha can make it harder for your body to fight infections. See your doctor regularly. Tell him or her if you have side effects.
SIMPONI® is not for everyone. Only your doctor can decide if SIMPONI® is right for you.