SIMPONI® is a treatment that can help control inflammation in your body—the source of ankylosing spondylitis (AS) symptoms.

Keep in mind that there are many factors to consider when treating a condition. Talk to your doctor about treatment options and what might be right for you.

  • SIMPONI® is given as a 50-mg injection under the skin (subcutaneous injection) once a month
  • SIMPONI® may be given with or without methotrexate or other nonbiologic disease-modifying antirheumatic drugs (DMARDs)
  • Corticosteroids, nonbiologic DMARDs, and/or non-steroidal anti-inflammatory drugs (NSAIDs) may be continued during treatment with SIMPONI®

If your doctor decides that you or a caregiver may be able to give your injections of SIMPONI® at home, you should receive training on the right way to prepare and inject SIMPONI®. Do not try to inject SIMPONI® yourself until you have been shown the right way to give the injections by your doctor or nurse. Use SIMPONI® exactly as prescribed by your doctor. Your doctor will tell you how much SIMPONI® to inject and when to inject it depending on your medical condition.

ABOUT SIMPONI®

Understanding AS

Knowing more can help you talk with your doctor about treatment options and what might be right for you.

LEARN ABOUT AS

SIMPONI® is a TNF blocker injection taken under the skin once a month for adults with active ankylosing spondylitis

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STARTING AND CONTINUING SIMPONI®

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1 injection under the skin once a month

Important Considerations in SIMPONI® Treatment:

What should I tell my doctor before starting treatment with SIMPONI®?

SIMPONI® may not be right for you. See “What is the most important information I should know about SIMPONI®?” in the Medication Guide for SIMPONI®. Before starting SIMPONI®, tell your doctor about all your medical conditions, including if you:

  • have an infection
  • have or have had lymphoma or any other type of cancer
  • have or had heart failure
  • have or have had a condition that affects your nervous system, such as multiple sclerosis or Guillain-Barré syndrome
  • have recently received or are scheduled to receive a vaccine. People taking SIMPONI® should not receive live vaccines or treatment with a weakened bacteria (such as BCG for bladder cancer). People taking SIMPONI® can receive non-live vaccines
  • have a baby and you were using SIMPONI® during your pregnancy. Tell your baby’s doctor before your baby receives any vaccine. Your baby may have an increased chance of getting an infection for up to 6 months after birth
  • are allergic to rubber or latex. The needle cover on the prefilled syringe and SmartJect® autoinjector contains dry natural rubber
  • are pregnant or planning to become pregnant. It is not known if SIMPONI® will harm your unborn baby
  • are breastfeeding or plan to breastfeed. You and your doctor should decide if you will take SIMPONI® or breastfeed

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially, tell your doctor if you:

  • use Orencia® (abatacept) or Kineret® (anakinra). You should not take SIMPONI® while you are also taking Orencia® (abatacept) or Kineret® (anakinra)
  • use other TNF-blocker medicines, including REMICADE® (infliximab), Humira® (adalimumab), Enbrel® (etanercept), or Cimzia® (certolizumab pegol)
  • receive Rituxan® (rituximab) or Actemra® (tocilizumab)

Ask your doctor if you are not sure if your medicine is one listed above.

Keep a list of all your medicines with you to show your doctor and pharmacist each time you get a new medicine.

Once you and your doctor have decided that SIMPONI® is right for you, J&J withMe will help you find the resources you may need to get started and stay on track. We will give you information on your insurance coverage, potential out-of-pocket costs, and treatment support, and identify options that may help make your treatment more affordable.

If you have commercial or private health insurance and need help paying for SIMPONI®, the J&J withMe Savings Program may be able to help.

LEARN MORE

The support and resources provided by J&J withMe are not intended to provide medical advice, replace a treatment plan you receive from your doctor or nurse, or serve as a reason for you to start or stay on treatment.