How to Take SIMPONI®

If your doctor decides to treat you with SIMPONI®, you will need to be trained on the proper way to self-inject SIMPONI® directly under the skin. Then you can inject SIMPONI® in the comfort of your home — just once each month — without having to travel to your doctor’s office for your injection. To learn more, click on a tab below.

The flexibility to choose.

For those who prefer a prefilled syringe, SIMPONI® offers that choice too. As with the SmartJect® autoinjector, the first time you use it should be in your doctor’s office with the help of a doctor or nurse. The prefilled syringe, just like the SmartJect® autoinjector, provides the convenience of injecting on your own, in the comfort and privacy of your home.

The prefilled syringe has been awarded the "Ease-of-Use Commendation" by the Arthritis Foundation®.Ease-of-Use Commendation

Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI® under the skin, just once a month.

Prefilled Syringe Demonstration Video

Watch the video to review the steps for injecting your SIMPONI® medication with the prefilled syringe. The injection demonstration video and guide are not meant to replace the Instructions for Use that come with your SIMPONI® medication. Please read those instructions prior to injecting your SIMPONI® medication.

Updates in Progress


Get Guide

Get a helpful guide for injecting with the Prefilled Syringe*

*Requires Adobe® Reader®, click here to download.

Selected Important Safety Information

SIMPONI® (golimumab) can lower your ability to fight infections. Serious and sometimes fatal events may occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Other possible serious side effects may include lymphoma, skin cancer, a rare and fatal cancer called hepatosplenic T-cell lymphoma, other cancers, hepatitis B, heart failure, nervous system problems, lupus-like syndrome, or allergic reactions. To learn more about these and other risks, please read the Important Safety Information and the Medication Guide, and talk with your doctor.

Next: Other Important Considerations