Treatment Support

SimponiOne® Support can help you get off to a good start. Choose from a variety of tools and services that can help you succeed in managing your treatment with SIMPONI®.

A SimponiOne® Care Coordinator can also refer you to a specialty pharmacy that can arrange for the prompt shipment of your medication to your home or other convenient location. Learn more about Treatment Support by clicking on a tab below.

¿Habla español?
SimponiOne® offers Spanish-speaking Care Coordinators.
SimponiOne® ofrece Coordinadores de Atención de habla hispana.

Your Safe Returns® pack arrives in the mail

Once-a-year return service for your once-monthly treatment with SIMPONI®.

SimponiOne® Safe Returns® combines a simple and safe way to dispose of your used SIMPONI® injection device immediately after each once-monthly treatment, with the convenience of a once-a-year return service — at no additional cost to you.


Safe Returns® gives you everything you need to properly dispose of your used SIMPONI® injection devices for a full year before mailing them back.


Placing your SmartJect® autoinjector or used syringe into the specifically designed Safe Returns® disposal container, tightening the lid securely, and storing it out of reach of children and pets, helps keep everyone safe.


The Safe Returns® container can hold 12 used SmartJect® autoinjectors, so you can return it for disposal just once a year — reducing the shipping materials you have to receive, paperwork you have to do, and trips to the post office you have to make, compared to the once-monthly Safe Returns® service. And because the Safe Returns® disposal container holds even more used syringes, you can return it for disposal even less frequently.

Here’s how Safe Returns® works

  • When you sign up, you’ll receive a Safe Returns® disposal container in the mail.
  • Follow the enclosed instructions for placing a used injection device into the disposal container after each once-monthly injection with SIMPONI®.
  • When your disposal container is full, after your 12th injection, contact SimponiOne® Support by phone, or click on the button below to request a Replacement Pack.
  • We’ll send you a Safe Returns® Replacement Pack with a new disposal container, along with everything you need to properly mail back your filled container for disposal.

Enrollin SimponiOne® Safe Returns®

Orderthe Safe Returns® Replacement Pack, with a new disposal container, along with everything you need to properly and easily return your filled container

Or call SimponiOne® Support at 877-MY SIMPONI (877-697-4676) Mon – Fri, 8:00 AM – 8:00 PM ET

Safe Returns® Instruction Guide

Please refer to the Safe Returns® Instruction Guide and contact your doctor with remaining questions regarding disposal of used SIMPONI® injection devices.

Download Guide

(Requires Adobe® Reader®, click here to download.)

Selected Important Safety Information

SIMPONI® (golimumab) can lower your ability to fight infections. Serious and sometimes fatal events may occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Other possible serious side effects may include lymphoma, skin cancer, a rare and fatal cancer called hepatosplenic T-cell lymphoma, other cancers, hepatitis B, heart failure, nervous system problems, lupus-like syndrome, or allergic reactions. To learn more about these and other risks, please read the Important Safety Information and the Medication Guide, and talk with your doctor.

Next: Getting Started