How to Take SIMPONI®

If your doctor decides to treat you with SIMPONI®, you will need to be trained on the proper way to self-inject SIMPONI® directly under the skin. Then you can inject SIMPONI® in the comfort of your home — just once each month — without having to travel to your doctor’s office for your injection. To learn more, click on a tab below.

Ease-of-Use CommendationSIMPONI® offers two easy-to-use injection options: the SmartJect® autoinjector, designed so you can self-inject without seeing the needle; or the prefilled syringe. Both have been awarded the Ease-of-Use Commendation by the Arthritis Foundation®. You and your doctor can decide which injection device is best for you.

SmartJect® AutoinjectorPrefilled Syringe

SIMPONI® is the first and only self-injectable biologic treatment for adults with active ankylosing spondylitis that requires just one injection each month.

Once you and your doctor are comfortable with the self-injection process, you will inject SIMPONI® under the skin, just once a month.

Just one injection, once a month.

SIMPONI® requires just one injection, once a month. That’s fewer monthly injections than any other anti-TNF biologic medication. While dosing frequency is important, there are other factors to consider. Talk to your doctor about which treatment is right for you.

Recommended dosing for self-injectable anti-TNF biologic medications for active ankylosing spondylitis.

*Indicated trademarks are the registered trademarks of their respective owners.

This presentation is not intended to compare the safety, effectiveness, or uses of these treatments. Please refer to each product’s Prescribing Information for recommended dosing and administration. SIMPONI®, as well as ENBREL® and HUMIRA®, are also available in a prefilled syringe.

It’s normal to have concerns about self-injecting.

For most people with moderate to severe RA, active psoriatic arthritis or active ankylosing spondylitis who participated in clinical trials, SIMPONI® injections were pain-free. Through 4 months of the studies, less than 1% of people treated with SIMPONI® reported experiencing any injection site pain, and 6% experienced injection site reactions, such as redness, swelling, itching, pain, bruising, or tingling. To learn more about these and other risks, please read the Important Safety Information about SIMPONI® below, and the Medication Guide, and talk with your doctor.

SimponiOne® Support offers tools to help you feel confident when self-injecting SIMPONI®, including the SmartJect® autoinjector reusable trainer. You can also access injection demonstration videos here. Janssen Nurse Support is also available 7 days a week to answer additional injection questions.

¿Habla español?
Janssen Nurse Support offers assistance in Spanish.
El soporte de enfermería de Janssen ofrece asistencia en español.

For more information on the proper way to inject SIMPONI®, please refer to the Instructions for Use that comes with your SIMPONI® medication.

Selected Important Safety Information

SIMPONI® (golimumab) can lower your ability to fight infections. Serious and sometimes fatal events may occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Other possible serious side effects may include lymphoma, skin cancer, a rare and fatal cancer called hepatosplenic T-cell lymphoma, other cancers, hepatitis B, heart failure, nervous system problems, lupus-like syndrome, or allergic reactions. To learn more about these and other risks, please read the Important Safety Information and the Medication Guide, and talk with your doctor.

Next: Other Important Considerations